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Biotechnology/Life Sciences is one of the most important applied sciences of the 21st century. Biotechnology is a field at the cutting edge of science and is a promising research oriented and fastest growing interdisciplinary field. It finds application in every sphere of life and has tremendous career opportunities available now and in future.
The ACADEMY provides you an advantage to enter into the most demanding disciplines in sciences which not just create degree but careers.

The ACADEMY was founded in year2005 by ex-IITian, to provide an invaluable opportunity for those brains who aspire for distinguished career in the field of biotechnology/life sciences.

gate sample questions


Candidates appearing in XL papers are required to answer three sections. Sections (H) i.e., Chemistry is compulsory. Candidates can choose any two out of the remaining sections (Biochemistry, Biotechnology, Botany, Microbiology, Zoology) mentioned.
• The choice of the appropriate paper is the responsibility of the candidate. However, some guidelines are suggested below:
Candidates are expected to appear in a paper appropriate to the discipline of their qualifying degree. However, the candidates are free to choose any paper according to their admission plan, keeping in mind the eligibility criteria of the admitting institute.
• The question paper of GATE will be fully of objective type.
Candidates have to mark the correct choice by darkening the appropriate bubble against each question on an Objective Response Sheet (ORS).
There will be ‘negative’ marking for wrong answers. The deduction will be 25% of the marks allotted.
The structure of the question paper.
XL paper contains a number of sections. Each Section is of 50 marks. Each Section will be fully objective type and the questions are divided into three groups.
Group I: Question Numbers 1 to 6 (6 questions) will carry one mark each (subtotal 6 marks).
Group II: Question numbers 7 to 24 (18 questions) will carry two marks each (subtotal 36 marks). Out of this, Q.23 and Q.24 may be common data based questions.
Group III: Question Numbers 25 to 28 (4 questions) will carry two marks each. These questions are called linked answer questions. These 4 questions comprise two pairs of questions (25 & 26 and 27 & 28). The solution to the second question of each pair (e.g. Q.26) will be linked to the correct answer to the first one (e.g. Q.25) in the pair (subtotal 8 marks).
All questions have four choices with only one being correct.
Wrong answers carry 25% negative marks. In Q.1 to Q.6 of each section, 0.25 mark will be deducted for each wrong answer and in Q.7 to Q.25 and Q.27, 0.5 mark will be deducted for each wrong answer. However, there is no negative marking in Q.26 and Q.28.


a. supply ribose 5–phosphate and NADPH
b. supply NADH and ATP
c. provide a mechanism to use the carbon skeletons of excess amino acids
d. provide carbon skeletons for oxidation of fatty acids

a. to add a nitrogenous base at the 5’ end of DNA
b. to add a nitrogenous base at the 3’ end of DNA
c. to add a phosphate at the 5’ end of DNA
d. to add a phosphate at the 3’ end of DNA

Qus. FOS, JUN and MYC are?
a. proteins expressed on the surface of cancerous cells
b. protein kinases that phosphorylate transcription factors in cancerous cells
c. proteins involved in regulation of expression of genes involved in growth promotion
d. proteins involved in ion transport in cancerous cells

Qus. Using microarray technique it was demonstrated that when a mammalian cell line was exposed to a drug, the expression of 10 genes in increased. Which of the following pairs of techniques could be used to validate microarray data?
a. southern blotting and polymerase chain reaction (PCR)
b. Northern blotting and fluorescence in situ hybridization
c. Southern blotting and reverse transcriptase (RT)-PCR
d. Northern blotting and RT-PCR

Qus. Which of the following statements is INCORRECT?
a. most of the eukaryotic mRNAs have a 7–methylguanosine cap at their 5’ end
b. TATA binding protein is involved in the synthesis of mRNA, tRNA and rRNA
c. Histones have no other function except in chromatin organization
d. Eukaryotic RNA polymerase II consists of more than 4 subunits

Qus. Which of the following statements about the mitochondrial proton gradient and membrane potential is correct?
a. Either of them is sufficient to make ATP from ADP + Pi
b. Both are required to make ATP
c. usually canel one another since the system is at equilibrium
d. neither of them is required for ATP synthesis

Qus. In the peptidoglycan layer of bacterial cell wall, which of the following pair of aminoacids are usually found in D-configuration
a. Alanine and glutamic acid
b. Alanine and lysine
c. Alanine and arginine
d. glutamic acid and lysine